When the immune system makes the mistake of identifying a normally harmless substance as damaging to the body, physiological reaction occurs. This reaction is called allergy.

In normal cases, the human body defends itself against harmful substances such as bacteria or viruses, but it also takes defensive position and aggressively attacks even harmless substances such as pollen, dust, or mold.

To attack and destroy the supposed enemy, the immune system generates large amounts of the antibodies called immunoglobin E (IgE) which is a complex chemical weapon. Each of the chemical weapon targets a specific allergen (the substance that causes the allergy). Some unpleasant (fatal in extreme cases) symptoms can be experienced by allergy-prone person, and inflammatory chemical like histamines, cytokines, and leukotrienes are released or produced in this disease-fighting process.

Itchy eyes, palate to skin rash, and a runny nose are all the possible signs of allergy. Allergy affects sense of tastes, sight, smell, and touch which causes irritation, extreme disability and sometimes life-threatening d.

Allergy to medication such as penicillin, Wasp Venom Allergy, Allergic Conjunctivitis, Food Allergy, Hives or Urticaria, Contact Dermatitis, Atopic Eczema, Hayfever or Allergic Rhinitis, and Asthma are the common allergic manifestations.

Historically, the term and concept of “allergy” was coined by a Viennese pediatrician named Clemens Von Pirquet in 1906. He came to the conclusion that the symptoms shown by some of his patients might be because of an outside allergen such as certain foods, pollen, or dust. Improper action of inflammatory immunoglobulin class IgE was believed to be the source of all hypersensitivities. However it soon became clear that several different mechanisms utilizing different effector molecules were responsible for allergy.